#SCAFFOLD TISSUE ENGINEERING SERIES#

Finally, we conclude with a discussion of the future for these fields.įunction of the human body is dependent on tubular tissues and tissue structures. We discuss state-of-the-art models within the context of vascular, intestinal, and tracheal tissue engineering. We categorize methods for manufacturing tubular scaffolds as follows: casting, electrospinning, rolling, 3D printing, and decellularization.

#SCAFFOLD TISSUE ENGINEERING SERIES#

We provide an overview of the general structure and anatomy for these tissue systems along with a series of general design criteria for tubular tissue engineering. In this review, we discuss some of the most common tissue engineered applications within the context of tubular tissues and the methods by which these structures can be produced. As such, the field has converged on a series of manufacturing techniques for producing these structures. Production of tubular scaffolds for different tissue engineering applications possesses many commonalities, such as the necessity for producing an intact tubular opening and for formation of semi-permeable epithelia or endothelia. As the field of tissue engineering has developed, numerous benchtop models have been produced as platforms for basic science and drug testing. Many of these hollow or tubular systems, such as vasculature, the intestines, and the trachea, are common targets for tissue engineering, given their relevance to numerous diseases and body functions. Hollow organs and tissue systems drive various functions in the body.

Scaffold tissue engineering